

MOTS-c
Mitochondrial-derived peptide studied in metabolic-regulation models.
In stock · ships same day on orders before 2pm ET
| Quantity | Per unit | You save |
|---|---|---|
| 3 to 4 units | $93.00 | 7% |
| 5 to 9 units | $89.00 | 11% |
| 10+ units | $84.00 | 16% |
Verify lot MC-2609-E in the COA library · This month's lot report
Ships same day on orders before 2pm ET. For laboratory research use only. Not for human or animal consumption.
Supplies researchers add to this order


What is MOTS-c?
MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial genome rather than the nucleus, one of a small family of mitochondrial-derived peptides. It is studied as a signalling molecule that links mitochondrial state to metabolic regulation, exercise response and cellular stress pathways such as AMPK. Pepstral supplies MOTS-c as a lyophilized powder, 10 mg net peptide per vial, with the certificate for the current lot published before listing.
→Read the full MOTS-c research guide
What is MOTS-c studied for?
- AMPK activation and metabolic-regulation assays
- Skeletal muscle and exercise-response models
- Insulin-sensitivity and glucose-uptake studies
- Mitochondrial-derived peptide signalling research
All applications above are in-vitro or preclinical research contexts. MOTS-c is sold for laboratory research only and is not for human or animal use.
What does the certificate for lot MC-2609-E show?
Every lot of MOTS-c is tested by an independent US laboratory before it is listed. The report for lot MC-2609-E is in the COA library and the lot number printed on the vial matches it. The current results:
| Test | Method | Lot MC-2609-E result |
|---|---|---|
| Identity | LC-MS | Matches the calculated mass for the sequence |
| Purity | HPLC-UV, 220 nm | 99.1% |
| Net peptide content | Amino acid analysis | Stated per vial on the certificate |
| Endotoxin | LAL, chromogenic | < 0.5 EU/mg |
| Sterility | USP <71> | Pass |
How is MOTS-c handled and stored?
Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within the 28-day window on the certificate. The reconstitution guide covers volumes and syringe units and the concentration table gives the numbers for this vial.
Frequently asked questions
What makes MOTS-c different from other peptides in the catalog?
It is encoded by mitochondrial DNA, in the 12S rRNA region, which is why it is used in studies of mitochondria-to-nucleus signalling.
What purity does lot MC-2609-E show?
99.1% by HPLC-UV, identity confirmed by LC-MS, endotoxin below 0.5 EU per mg.
Is MOTS-c in a bundle?
Yes. The Longevity stack pairs it with GHK-Cu and NAD+ at a 10% saving.
Is MOTS-c for human use?
No. Every product on this site is sold for in-vitro laboratory research only and is not for human or animal consumption, diagnostic or therapeutic use.
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