from$105
GLP-1 & Metabolic · SKU SEMA-5
Semaglutide
GLP-1 receptor agonist for in-vitro metabolic and appetite-signalling research.
$ 60 per 5 mg vial · free shipping over $300
Size
In stock · ships same day on orders before 2pm ET
Purity (HPLC-UV)≥99.6% on lot SM-2608-B
IdentityConfirmed by LC-MS
FormLyophilized powder, sealed vial
Endotoxin< 0.5 EU/mg (LAL)
Storage-20°C sealed · 2-8°C reconstituted
CertificateView COA for SM-2608-B →
CAS number910463-68-2
Molecular formulaC187H291N45O59
Molecular weight4114 g/mol
Residues31
PubChemCID 56843331
Volume pricing, applied automatically in the cart
| Quantity | Per unit | You save |
|---|---|---|
| 3 to 4 units | $55.80 | 7% |
| 5 to 9 units | $53.40 | 11% |
| 10+ units | $50.40 | 16% |
Verify lot SM-2608-B in the COA library · This month's lot report
Ships same day on orders before 2pm ET. For laboratory research use only. Not for human or animal consumption.
Frequently bought together
Supplies researchers add to this order
Reconstitution solution30 mL · $25
Reconstitution kitKit · $49.99
What is Semaglutide?
Semaglutide is a GLP-1 receptor agonist, a 31-residue analogue of the native hormone modified with a fatty-acid side chain that extends its half-life. It is the most widely characterised compound in the incretin class, which makes it the standard comparator in metabolic, appetite-signalling and glucose-regulation research. Pepstral supplies semaglutide as a lyophilized powder, 5 mg net peptide per vial, with every lot tested independently before it is listed.
→Read the full Semaglutide research guide
What is Semaglutide studied for?
- GLP-1 receptor activation and receptor-internalisation assays
- Glucose-dependent insulin secretion models
- Central appetite-signalling pathways
- Reference compound for newer incretin peptides
All applications above are in-vitro or preclinical research contexts. Semaglutide is sold for laboratory research only and is not for human or animal use.
What does the certificate for lot SM-2608-B show?
Every lot of Semaglutide is tested by an independent US laboratory before it is listed. The report for lot SM-2608-B is in the COA library and the lot number printed on the vial matches it. The current results:
| Test | Method | Lot SM-2608-B result |
|---|---|---|
| Identity | LC-MS | Matches the calculated mass for the sequence |
| Purity | HPLC-UV, 220 nm | 99.6% |
| Net peptide content | Amino acid analysis | Stated per vial on the certificate |
| Endotoxin | LAL, chromogenic | < 0.5 EU/mg |
| Sterility | USP <71> | Pass |
How is Semaglutide handled and stored?
Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within the 28-day window on the certificate. The reconstitution guide covers volumes and syringe units and the concentration table gives the numbers for this vial.
Frequently asked questions
Why is semaglutide the usual comparator in incretin studies?
It has the largest published dataset in the class, so new dual- and triple-agonist compounds are benchmarked against it.
What does the certificate for lot SM-2608-B show?
99.6% purity by HPLC-UV, identity by LC-MS matching the target mass, endotoxin below 0.5 EU per mg, and net peptide content by amino-acid analysis.
Does the fatty-acid side chain affect reconstitution?
It makes the peptide slower to dissolve. Add the water down the wall of the vial and allow a few minutes with gentle swirling before drawing.
Is Semaglutide for human use?
No. Every product on this site is sold for in-vitro laboratory research only and is not for human or animal consumption, diagnostic or therapeutic use.
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