

Retatrutide
Triple-agonist research peptide (GIP, GLP-1, glucagon receptor activity) in a single lot-matched vial.
In stock · ships same day on orders before 2pm ET
| Quantity | Per unit | You save |
|---|---|---|
| 3 to 4 units | $97.65 | 7% |
| 5 to 9 units | $93.45 | 11% |
| 10+ units | $88.20 | 16% |
Verify lot RT-2609-A in the COA library · This month's lot report
Ships same day on orders before 2pm ET. For laboratory research use only. Not for human or animal consumption.
Supplies researchers add to this order


What is Retatrutide?
Retatrutide is a synthetic 39-residue peptide that acts on three receptors at once: GIP, GLP-1 and the glucagon receptor. Researchers use it to study how combined incretin and glucagon signalling changes energy balance, glucose handling and adipose tissue in cell and animal models, and to compare triple-agonist activity against the single- and dual-agonist peptides that came before it. Pepstral supplies it as a lyophilized powder, 10 mg net peptide per vial, with the lot-matched certificate published before the vial is listed.
→Read the full Retatrutide research guide
What is Retatrutide studied for?
- Incretin receptor pharmacology and receptor-selectivity assays
- Energy expenditure and adiposity models
- Glucose regulation and insulin-sensitivity studies
- Head-to-head comparisons with semaglutide and tirzepatide
All applications above are in-vitro or preclinical research contexts. Retatrutide is sold for laboratory research only and is not for human or animal use.
What does the certificate for lot RT-2609-A show?
Every lot of Retatrutide is tested by an independent US laboratory before it is listed. The report for lot RT-2609-A is in the COA library and the lot number printed on the vial matches it. The current results:
| Test | Method | Lot RT-2609-A result |
|---|---|---|
| Identity | LC-MS | Matches the calculated mass for the sequence |
| Purity | HPLC-UV, 220 nm | 99.4% |
| Net peptide content | Amino acid analysis | Stated per vial on the certificate |
| Endotoxin | LAL, chromogenic | < 0.5 EU/mg |
| Sterility | USP <71> | Pass |
How is Retatrutide handled and stored?
Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within the 28-day window on the certificate. The reconstitution guide covers volumes and syringe units and the concentration table gives the numbers for this vial.
Frequently asked questions
What is the difference between retatrutide and tirzepatide?
Tirzepatide acts on two receptors, GIP and GLP-1. Retatrutide adds glucagon receptor activity, which is why it appears in studies of energy expenditure as well as glucose signalling.
Is the 10 mg on the label gross weight or net peptide?
Net peptide. The certificate reports amino-acid analysis, so the mass on the label is peptide rather than counter-ions or residual water.
How is retatrutide reconstituted for research use?
Bacteriostatic water is added slowly down the vial wall, then the vial is swirled, never shaken. 10 mg in 2 mL gives 5 mg/mL; the reconstitution guide covers other volumes.
Is Retatrutide for human use?
No. Every product on this site is sold for in-vitro laboratory research only and is not for human or animal consumption, diagnostic or therapeutic use.
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