Lyophilized peptides are routinely shipped at ambient temperature, and the science says that is fine. This post explains why the dry state is stable, what actually threatens a vial in transit, when cold shipping is genuinely warranted, and what to do with a package that arrived warm.
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A 5 mg vial of lyophilized peptide holds a few milligrams of powder, often a thin film or a small cake you can barely see. That is normal. Here is what freeze-drying leaves behind, what a good vial looks like, the appearances that are fine, the ones that are not, and what to do before you open it.
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The same compound can cost half as much from one supplier as another. Sequence length, purification passes, net peptide content, per-lot testing and fill accuracy explain most of the gap. Here is where each shows up on the certificate, with a worked price-per-net-milligram comparison.
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Semaglutide, tirzepatide and retatrutide carry a fatty-acid side chain that makes them bind albumin and last for days. The same chain makes the lyophilized powder slow to wet and dissolve. What the chain is, why it slows dissolution, and a reconstitution method that works without shaking.
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Almost every research peptide arrives as a trifluoroacetate salt, because TFA is used to cleave and purify it. The counter-ion is part of the powder's weight and, for some cell work, part of the result. What the salt form is, how much TFA a given peptide can carry, the evidence that it affects cells, and when to ask for acetate.
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One table with the residue count, molecular formula, molecular weight and PubChem record for every compound in the catalog, pulled from PubChem on 11 September 2026. Plus the expected mass-spectrometry peaks at three charge states and the molar concentration of each catalog vial at three reconstitution volumes.
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One table giving the receptor or molecular target for every compound in the catalog, with the primary paper that established it. Five compounds act at named receptors; the rest work through actin binding, copper delivery, a mitochondrial pathway or as a cofactor. Which is which, and what it means for an assay.
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A blend fixes the ratio and saves a vial; single compounds let you vary the ratio and run each arm alone. Choose the blend when the ratio comes from prior work and the singles when the ratio is the question. With the four-arm design, reconstitution arithmetic at three volumes, and how to read a blend certificate.
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NAD+ is a dinucleotide cofactor, not a peptide, and it behaves differently on the bench. It is used at millimolar concentrations, it is hygroscopic as a powder, and in solution its stability depends on the buffer far more than on temperature. What the 2024 stability data show, how to store the powder, and how to make and keep a stock.
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Research peptides are sold in the US as laboratory chemicals, not as drugs. The line is intended use: a peptide sold and used for research is regulated differently from the same peptide sold or used for human treatment. Here is how the FDA framework works, what changed in 2026, what the 2026 warning letters say, and what it means for a buyer.
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98% purity by HPLC is enough for most in-vitro work and is the floor for cell assays and animal models. Below it, the missing percent is usually truncated sequences, which matters more for some experiments than others. Thresholds by application, a worked chromatogram, and the current figure for every lot we sell.
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Three research compounds act on the growth hormone axis by two different routes. Ipamorelin is a five-residue secretagogue at the GHS receptor; CJC-1295 and tesamorelin are GHRH analogues at the GHRH receptor, one long-acting through albumin binding and one through an N-terminal modification. Receptor, size, duration and the literature for each, and how the three combine in a design.
Read the post →The blog covers buying, handling and research-design questions as they come up. The evergreen material lives in the guides: reconstitution, reading a certificate of analysis, storage and stability, one research guide per compound and the glossary.
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