

IGF-1 LR3 1 mg
Long arginine-3 IGF-1 analogue with reduced binding-protein affinity.
In stock · ships same day on orders before 2pm ET
| Quantity | Per unit | You save |
|---|---|---|
| 3 to 4 units | $79.05 | 7% |
| 5 to 9 units | $75.65 | 11% |
| 10+ units | $71.40 | 16% |
Verify lot IGF-2609-X in the COA library · This month's lot report
Ships same day on orders before 2pm ET. For laboratory research use only. Not for human or animal consumption.
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What is IGF-1 LR3?
IGF-1 LR3 is an 83-amino-acid analogue of insulin-like growth factor 1, carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Both changes reduce its affinity for IGF binding proteins, so more of it stays free in a culture system than native IGF-1 would. Pepstral supplies it as a lyophilized powder for in-vitro laboratory research only.
What is IGF-1 LR3 studied for?
- IGF-1 receptor binding assays
- Cell proliferation and differentiation models
- Binding-protein interaction studies
- Comparisons against native IGF-1
All applications above are in-vitro or preclinical research contexts. IGF-1 LR3 is sold for laboratory research only and is not for human or animal use.
What does the certificate for lot IGF-2609-X show?
Every lot of IGF-1 LR3 is tested by an independent US laboratory before it is listed. The report for lot IGF-2609-X is in the COA library and the lot number printed on the vial matches it. The current results:
| Test | Method | Lot IGF-2609-X result |
|---|---|---|
| Identity | LC-MS | Matches the calculated mass for the sequence |
| Purity | HPLC-UV, 220 nm | 99.0% |
| Net peptide content | Amino acid analysis | Stated per vial on the certificate |
| Endotoxin | LAL, chromogenic | < 0.5 EU/mg |
| Sterility | USP <71> | Pass |
How is IGF-1 LR3 handled and stored?
Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within the 28-day window on the certificate. The reconstitution guide covers volumes and syringe units and the concentration table gives the numbers for this vial.
Frequently asked questions
Why the LR3 modification?
Native IGF-1 is largely bound by IGF binding proteins. The arginine-3 substitution and the N-terminal extension lower that affinity, so a larger free fraction is available in the system.
Is it more potent than IGF-1?
In systems containing binding proteins it behaves as though it were, because more remains free. In a binding-protein-free assay the difference narrows.
Is IGF-1 LR3 for human use?
No. Every product on this site is sold for in-vitro laboratory research only and is not for human or animal consumption, diagnostic or therapeutic use.
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