

IGF-1 LR3 1 mg
Long arginine-3 IGF-1 analogue with reduced binding-protein affinity.
In stock · ships same day on orders before 2pm ET
Wholesale pricing starts at 25 vials per SKU, with net-30 terms for verified institutions. It is quoted per order rather than applied in the cart — ask for a wholesale quote.
Every lot of IGF-1 LR3 in the COA library · Latest lot report
Ships same day on orders before 2pm ET. For laboratory research use only. Not for human or animal consumption.
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What is IGF-1 LR3?
IGF-1 LR3 is an 83-amino-acid analogue of insulin-like growth factor 1, carrying an arginine substitution at position 3 and a 13-residue N-terminal extension. Both changes reduce its affinity for IGF binding proteins, so more of it stays free in a culture system than native IGF-1 would. Pepstral supplies it as a lyophilized powder for in-vitro laboratory research only.
→Read the full IGF-1 LR3 research guide
What is IGF-1 LR3 studied for?
- IGF-1 receptor binding assays
- Cell proliferation and differentiation models
- Binding-protein interaction studies
- Comparisons against native IGF-1
All applications above are in-vitro or preclinical research contexts. IGF-1 LR3 is sold for laboratory research only and is not for human or animal use.
What does the certificate for lot IGF1-0803 show?
Every lot of IGF-1 LR3 is tested by an independent US laboratory before it is listed. The report for lot IGF1-0803 is in the COA library and the lot number printed on the vial matches it. The current results:
| Test | Method | Lot IGF1-0803 result |
|---|---|---|
| Identity | LC-MS/MS | IGF-1 LR3 · conforms |
| Content | HPLC quantitation | 1.12 mg |
| Purity | RP-HPLC (214 nm) | 99.55% |
| Endotoxin | USP <85> | <0.05 EU/mL |
| Heavy metals | USP <232> | <0.01 ppm |
How is IGF-1 LR3 handled and stored?
Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within our 28-day default for a preserved solution. The concentration table gives the dilution volumes and microlitre aliquots for this vial.
Frequently asked questions
Why the LR3 modification?
Native IGF-1 is largely bound by IGF binding proteins. The arginine-3 substitution and the N-terminal extension lower that affinity, so a larger free fraction is available in the system.
Is it more potent than IGF-1?
In systems containing binding proteins it behaves as though it were, because more remains free. In a binding-protein-free assay the difference narrows.
Is IGF-1 LR3 for human use?
No. Every product on this site is sold for in-vitro laboratory research only and is not for human or animal consumption, diagnostic or therapeutic use.
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