What is adamax, and what is known about it?
Adamax is a synthetic peptide described by its sellers as semax carrying an adamantane-containing group. No public registry record has been confirmed for it, and the published literature is essentially absent; what is known here comes from the certificate, whose identity line reports a mass of 1032.3, which is 218 daltons above semax's 813.9 and consistent with an adamantane-based modification. This guide records that and nothing more. The material is for in-vitro research only.
What is the structure of Adamax?
The certificate mass of 1032.3 is the one hard fact. Semax is Met-Glu-His-Phe-Pro-Gly-Pro at 813.9; the difference of about 218 daltons corresponds to an adamantane-containing acyl group with a short linker, which is how vendors describe the molecule. The exact attachment point and linker are not documented in any source this site can cite, so the formula and CAS fields are blank. The adamantane post explains what such a group does to a peptide in general terms.
| Identifier | Value |
|---|---|
| Molecular formula | not recorded |
| Molecular weight | not recorded |
| Residues | not recorded |
| CAS number | not recorded |
| PubChem CID | not recorded |
| Current lot | ADA10-0803 |
How is Adamax thought to work?
Not established. If the semax backbone is intact, the parent's reported neurotrophin-related effects in rodents may apply; the adamantane group is expected, from analogous compounds, to increase lipophilicity and resistance to peptidases. Neither has been demonstrated for this molecule in a citable study.
Which research areas use Adamax?
| Area | Typical models and endpoints |
|---|---|
| Semax analogue comparisons | Side-by-side assays with semax and N-acetyl semax amidate, which is the only research use this site can describe. |
| Peptidomimetic stability | Adamantylation as a general strategy, studied through better-documented examples such as P-21. |
| Analytical identity | A molecule whose identity rests entirely on the certificate's measured mass. |
What does the published literature show?
There is no peer-reviewed literature on adamax that this site can cite. The adamantane-and-semax comparison post sets out what can be inferred from the parent compounds. Any methods section should record the supplier, lot and certificate mass, because no registry identifier exists to cite.
How is Adamax handled in the laboratory?
Dissolves in water with swirling; the adamantane group adds hydrophobicity, so a small fraction of organic co-solvent may help at high concentration. The semax backbone contains methionine: protect from light and air. Store lyophilized at minus 20 °C; aliquot and freeze. The concentration table covers volumes and syringe units; the storage guide covers stability by compound class.
What does the current certificate show?
Lot ADA10-0803 tested at 99.78% purity by RP-HPLC (214 nm), identity confirmed by LC-MS/MS, endotoxin <0.05 EU/mL. The certificate is in the COA library and the lot number on the vial matches it. Sold as 10 mg per vial at $90, for laboratory research only.
Certificate history for Adamax
Every certificate the library holds for this compound, newest first. A replaced lot stays listed so the history can be read; the certificate dataset reads all 114 together.
| Lot | Issued | Size | Identity | Purity | Content | Status |
|---|---|---|---|---|---|---|
| ADA10-0803 | Aug 17, 2026 | 10 mg | LC-MS/MS | 99.78% | 10.39 mg | Current |
Frequently asked questions
Why is so little stated here?
Because so little is documented. The editorial policy is to say what the certificate shows and leave the rest blank rather than fill it with claims from other vendors' pages.
What does the current certificate show?
Lot ADA10-0803: identity by LC-MS/MS at 1032.3, purity 99.78% by RP-HPLC at 214 nm, content 10.39 mg, endotoxin below 0.05 EU/mL. Issued 17 August 2026.
How does it relate to semax?
By vendor description and by mass: 1032.3 is semax plus about 218 daltons, consistent with an adamantane-containing group. The comparison post goes through the arithmetic.
References
- Dolotov OV, Karpenko EA, Inozemtseva LS, et al. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Res. 2006;1117(1):54-60.
- Pepstral certificate COA for lot ADA10-0803, Bioviridian Inc., issued 17 August 2026; the sole primary source for this molecule's mass.
Clinical results cited above describe regulated trials of pharmaceutical products and are given as context for research interest only. Nothing on this page describes or recommends use of the material sold here in humans or animals.
Adamax 10 mg
$90 per vial
Lot ADA10-0803 · 99.78% RP-HPLC (214 nm) · certificate published
View productRelated
- Semax research guide · Semax 10 mg
- Selank research guide · Selank 10 mg
- Adamax and Semax: what separates them
- What adamantane conjugation does to a peptide
- Semax vs N-acetyl Semax amidate: what the acetyl and the amide change
- P-21: the CNTF-derived peptide, what its certificate reports, and why the same lot was certified twice
- Glossary of certificate terms
