Dihexa 5 mg

What is Dihexa?

Dihexa is a synthetic derivative of angiotensin IV, studied for its interaction with hepatocyte growth factor and the c-Met receptor. It was designed for metabolic stability and blood-brain-barrier penetration relative to the parent peptide. Pepstral supplies it as a lyophilized powder for in-vitro laboratory research only.

→Read the full Dihexa research guide

What is Dihexa studied for?

• HGF and c-Met receptor assays
• Synaptogenesis models
• Angiotensin IV derivative comparisons
• Neuroplasticity research

All applications above are in-vitro or preclinical research contexts. Dihexa is sold for laboratory research only and is not for human or animal use.

What testing does Dihexa carry?

No laboratory certificate for Dihexa is published in the COA library yet. Our other lots are tested by an independent US laboratory for identity, content, purity and endotoxin before listing, and we will not claim results for this one that we cannot show you. Ask us for the lot report before ordering and we will send the one that matches the vial you receive.

How is Dihexa handled and stored?

Sealed vials are stored at -20°C away from light and keep for 24 months. To reconstitute, add bacteriostatic water slowly down the inside wall of the vial and swirl until clear; never shake. Once in solution, keep at 2 to 8°C and use within our 28-day default for a preserved solution. The concentration table gives the dilution volumes and microlitre aliquots for this vial.

Frequently asked questions

Related reading

• Dihexa is not a peptide, and the parts that are not amino acids are the parts that make it workDihexa is a peptidomimetic derived from angiotensin IV. Two of its four components are not amino acids, and that is what keeps it from being degraded.
• P-21: the CNTF-derived peptide, what its certificate reports, and why the same lot was certified twiceP-21 is a short peptide from the active region of ciliary neurotrophic factor. What its certificate reports, and why one lot carries two documents.
• PE-22-28: the spadin fragment, the TREK-1 channel, and what a 10 mg certificate showsPE-22-28 is a seven-residue fragment of spadin acting at the TREK-1 channel. Where the sequence comes from, and what a 10 mg certificate shows.
• The disulphide bridge in oxytocin, and why it dictates storageOxytocin is nine residues closed by one disulphide bridge, and that single bond is what dictates how the vial must be stored and handled.